Glial reprogramming papers

  • A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia

    Amy Tresenrider, Marcus Hooper, Levi Todd, Faith Kierney, Nicolai Blasdel, Cole Trapnell, Thomas A. Reh - 2023 - eLife

    Link

  • Controlling donor and newborn neuron migration and maturation in the eye through microenvironment engineering

    Jonathan R. SoIucy, Levi Todd, Emil Kriukova, Monichan Phaya, Volha V. Malechkaa, John Dayron Riveraa, Thomas A. Reh and Petr Baranov 2023 - PNAS

    Link

  • Reprogramming Müller glia to regenerate ganglion-like cells in adult mouse retina with developmental transcription factors

    Levi Todd, Wesley Jenkins, Connor Finkbeiner, Marcus J. Hooper, Phoebe Donaldson, Marina Pavlou, Juliette Wohlschlegel, Norianne Ingram, Fred Rieke & Thomas Reh - 2022 Science Advances

    Link

  • Efficient stimulation of retinal regeneration from Müller glia in adult mice using combinations of proneural bHLH transcription factors

    Levi Todd, Marcus Hooper, Alex Haugan, Connor Finkbeiner, Nikolas Jorstad, Nicholas Radulovich, Claire Wong, Phoebe Donaldson, Wesley Jenkins, Qiang Chen, Fred Rieke, Thomas Reh - 2021 Cell Reports

    Link

  • Comparative Biology of Vertebrate Retinal Regeneration: Restoration of Vision through Cellular Reprogramming

    Levi Todd & Thomas Reh - 2021 Cold Spring Harbor Perspectives In Biology

    Link

  • STAT signaling modifies Ascl1 chromatin binding and limits neural regeneration from muller glia in adult mouse retina

    Nikolas Jorstad*, Matthew Wilken*, Levi Todd*, Connor Finkbeiner, Paul Nakamura, Nicholas Radulovich, Marcus Hooper, Alex Chitsazan, Brent Wilkerson, Fred Rieke & Thomas A Reh - 2020 Cell Reports

    Link

  • Gene regulatory networks controlling vertebrate retinal regeneration

    Thanh Hoang, Jie Wang, Patrick Boyd, Fang Wang, Clayton Santiago, Lizhi Jiang, Sooyeon Yoo, Manuela Lahne, Levi Todd, Meng Jia, Cristian Saez, Casey Keuthan, Isabella Palazzo, Natalie Squires, Warren A Campbell, Fatemeh Rajaii, Trisha Parayil, Vickie Trinh, Dong Won Kim, Guohua Wang, Leah J Campbell, John Ash, Andy J Fischer, David R Hyde, Jiang Qian, Seth Blackshaw - 2020 Science

    Link

  • Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation

    Warren A Campbell IV, Ameya Deshmukh, Sydney Blum, Levi Todd, Ninoshka Mendonca, Jessica Weist, Joshua Zent, Thanh V Hoang, Seth Blackshaw, Jennifer Leight, Andy J Fischer - 2019 Experimental Neurology

    Link

  • Retinoic acid-signaling regulates the proliferative and neurogenic capacity of Müller glia-derived progenitor cells in the avian retina

    Levi Todd, Lilianna Suarez, Colin Quinn, Andy J Fischer - 2018 Stem Cells

    Link
    Selected for Cover!

  • BMP and TGFβ signaling regulate the formation of Müller glia derived progenitor cells in the avian retina

    Levi Todd, Isabella Palazzo, Natalie Squires, Ninoshka Mendonca, Andy Fischer - 2017 Glia

    Link

  • Jak/Stat signaling regulates the proliferation and neurogenic potential of Müller glia-derived progenitor cells in the avian retina

    Levi Todd, Natalie Squires, Lilianna Suarez, Andy Fischer - 2016 Scientific Reports

    Link

  • Wnt/β-catenin-signaling and the formation of Müller glia derived progenitors in the chick retina

    Donika Gallina, Isabella Palazzo, Lillia Steffenson, Levi Todd, Andy J Fischer - 2016 Developmental Neurobiology

    Link

  • mTor signaling is required for the formation of proliferating Müller glia-derived progenitor cells in the chick retina

    Christopher P Zelinka, Leo Volkov, Zachary A Goodman, Levi Todd, Isabella Palazzo, William A Bishop, Andy J Fischer - 2016 Development

    Link
    Selected for cover!

  • Heparin-binding EGF-like growth factor (HB-EGF) stimulates the proliferation of Müller glia-derived progenitor cells in avian and murine retinas

    Levi Todd, Leo Volkov, Chris Zelinka, Natalie Squires, Andy Fischer - 2015 Molecular and Cellular Neuroscience

  • Hedgehog signaling stimulates the formation of proliferating Müller glia-derived progenitor cells in the chick retina

    Levi Todd & Andy Fischer - 2015 Development

    Link

  • A comparative analysis of Müller glia-mediated regeneration in the vertebrate retina

    Donika Gallina, Levi Todd, Andy J Fischer - 2014 Experimental Eye Research

    Link

Neuro-immune papers

  • NFkB signaling promotes glial reactivity and suppresses Müller glia mediated neuron regeneration in the mammalian retina

    Isabella Palazzo, Levi Todd, Thanh V Hoang, Thomas A Reh, Seth Blackshaw, Andy J Fischer - 2022 Glia

    Link
    Selected for Cover!

  • Microglial depletion abolishes ischemic preconditioning in white matter

    Margaret A Hamner, Ashley McDonough, Davin C Gong, Levi Todd, German Rojas, Sibylle Hodecker, Christopher B Ransom, Thomas A Reh, Bruce R Ransom, Jonathan R Weinstein - 2022 Glia

    Link

  • Microglia suppress Ascl1-induced retinal regeneration in mice

    Levi Todd, Connor Finkbeiner, Claire Wong, Marcus Hooper & Thomas Reh - 2020 Cell Reports

    Link
    Selected for Cover!

  • Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina

    Levi Todd*, Isabella Palazzo*, Lilianna Suarez, Xiaoyu Liu, Leo Volkov, Thanh Hoang, Warren Campbell, Seth Blackshaw, Ning Quan &, Andy Fischer - 2019 Journal of Neuroinflammation

    Link here

  • Reactive microglia and macrophage facilitate the formation of Müller glia derived retinal progenitors

    Andy J Fischer, Christopher Zelinka, Donika Gallina, Melissa A Scott, Levi Todd - 2014 Glia

    Link

Other papers

  • Inducing Neural Regeneration from Glia Using Proneural bHLH Transcription Factors

    Levi Todd - 2023 Advances in Experimental Medicine and Biology

    Conference paper

  • Valproic Acid for a Treatment of Retinitis Pigmentosa: Reasons for Optimism and Caution

    Levi Todd and Christopher Zelinka - 2017 Journal of Neuroscience

    Link

  • Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques

    Sara E Gombash, Christopher J Cowley, Julie A Fitzgerald, Christina A Lepak, Mitchell G Neides, Kathryn Hook, Levi Todd, Guo-Du Wang, Christian Mueller, Brian K Kaspar, Eric C Bielefeld, Andrew J Fischer, Jackie D Wood, Kevin D Foust - 2017 Gene Therapy

    Link

  • Comparative analysis of glucagonergic cells, glia, and the circumferential marginal zone in the reptilian retina

    Levi Todd, Lilianna Suarez, Natalie Squires, Christopher Paul Zelinka, Kevin Gribbins, Andy J Fischer - 2016 Journal of Comparative Neurology

    Link